BackgroundBreast cancer patients are at elevated risk of depression during treatment, thus provoking the chance of poor clinical outcomes. This retrospective cohort study aimed to investigate whether integrating Chinese herbal medicines citation into conventional cancer therapy could decrease the risk of depression in the long-term breast cancer survivors.MethodsA cohort of patients aged 20–70 years and with newly diagnosed breast cancer during 2000–2008 was identified from a nationwide claims database. In this study, we focused solely on survivors of breast cancer at (...) least1 year after diagnosis. After one-to-one matching for age, sex, and baseline comorbidities, breast cancer patients who received and did not receive CHM treatment were enrolled. The incidence rate and hazard ratio citation for depression between the two groups was estimated at the end of 2012. A Cox proportional hazard model was constructed to examine the impact of the CHM use on the risk of depression.ResultsDuring the study period, the incidence rate of depression was significantly lower in the treated cohort than in the untreated cohort [8.57 compared with 11.01 per 1,000 person-years citation], and the adjusted HR remained significant at 0.74 in a Cox proportional hazards regression model. The corresponding risk further decreasing to 43% among those using CHM for more than 1 year.ConclusionFinding from this investigation indicated that the lower risk of depression observed in breast cancer patients treated with CHM, suggesting that CHM treatment should be considered for disease management toward breast cancer. Yet, the optimal administered dose should be determined in further clinical trials. (shrink)

Lower plasma levels of high-density lipoproteins in adolescents with type 2 diabetes have been associated with a higher pulse wave velocity, a marker of arterial stiffness. Evidence suggests that HDL proteins or particle subspecies are altered in T2D and these may drive these relationships. In this work, we set out to reveal any specific proteins and subspecies that are related to arterial stiffness in youth with T2D from proteomics data. Plasma and PWV measurements were previously acquired from lean and T2D (...) adolescents. Each plasma sample was separated into 18 fractions and evaluated by mass spectrometry. Then, we applied a validated network-based computational approach to reveal HDL subspecies associated with PWV. Among 68 detected phospholipid-associated proteins, we found that seven were negatively correlated with PWV, indicating that they may be atheroprotective. Conversely, nine proteins show positive correlation with PWV, suggesting that they may be related to arterial stiffness. Intriguingly, our results demonstrate that apoA-I and histidine-rich glycoprotein may reverse their protective roles and become antagonistic in the setting of T2D. Furthermore, we revealed two arterial stiffness-associated HDL subspecies, each of which contains multiple PWV-related proteins. Correlation and disease association analyses suggest that these HDL subspecies might link T2D to its cardiovascular-related complications. (shrink)

Innovation is a high-risk endeavor and success is dependent upon a firm's understanding of customer needs. A company's initial resistance to adopting innovation is mitigated with a solid foundation of customer trust in the firm. This book uniquely combines the work of scholars and practitioners to examine how trust and customer-centricity impacts every phase of the innovation journey.Adopting a multidisciplinary approach, the contributions in this collection consider different aspects of innovating for trust. Beginning with the notion of trust itself, authors (...) examine the importance of trust in futures thinking, business model innovation, service design, co-creation, the innovative organization and self-service technologies. The book also contains a valuable collection of case studies based upon innovation with major service providers, which supports the final emphasis on the importance of trust in commercializing innovations.Practical and engaging, Innovating for Trust will appeal to enlightened business managers aiming to build and maintain customer trust, as well as students and researchers of innovation, trust and strategy. (shrink)

Firms are central to wealth creation and distribution, but their role in economic inequality in a society remains poorly studied. In this essay, we define and distinguish value distribution from value creation and value appropriation. We identify four value distribution mechanisms that firms engage in and argue that shareholder wealth maximization approach skews the value distribution toward shareholders and top executives, which in turn contributes to rising economic inequalities around the world. We call on organizational scholars to study the value (...) distribution role of firms and its consequences for society, and introduce the articles in this volume of the special issue on economic inequality, business, and society. (shrink)

ObjectiveDespite its prevalence, insomnia disorder remains poorly understood. In this study, we used machine learning to analyze the functional connectivity disturbances underlying ID, and identify potential predictors of treatment response through recurrent transcranial magnetic stimulation and pharmacotherapy.Materials and methods51 adult patients with chronic insomnia and 42 healthy age and education matched controls underwent baseline anatomical T1 magnetic resonance imaging, resting-stage functional MRI, and diffusion weighted imaging. Imaging was repeated for 24 ID patients following four weeks of treatment with pharmacotherapy, with (...) or without rTMS. A recently developed machine learning technique, Hollow Tree Super was used to classify subjects into ID and control groups based on their FC, and derive network and parcel-based FC features contributing to each model. The number of FC anomalies within each network was also compared between responders and non-responders using median absolute deviation at baseline and follow-up.ResultsSubjects were classified into ID and control with an area under the receiver operating characteristic curve of 0.828. Baseline FC anomaly counts were higher in responders than non-responders. Response as measured by the Insomnia Severity Index was associated with a decrease in anomaly counts across all networks, while all networks showed an increase in anomaly counts when response was measured using the Pittsburgh Sleep Quality Index. Overall, responders also showed greater change in all networks, with the Default Mode Network demonstrating the greatest change.ConclusionMachine learning analysis into the functional connectome in ID may provide useful insight into diagnostic and therapeutic targets. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Remembering Lewis E. HahnGeorge C. H. Sun, President, John Howie, Professor Emeritus, Thomas Alexander, Professor and Director of Graduate Studies, Kenneth W. Stikkers, Professor and Chair, Randall Auxier, Professor, Robert Hahn, Professor, Joseph Wu, Professor Emeritus, Elizabeth R. Eames, Professor Emeritus, Martin Lu, Professor of Philosophy, George Kimball Plochmann, Professor Emeritus, Matt Sronkoski, Philosophy Graduate and Academic Adviser, Dave Clarke, Professor Emeritus, Eugenie Gatens-Robinson, Professor Emerita, Hans H. Rudnick, (...) Professor Emeritus, Stephen Bickham, Professor EmeritusPresident, and Don Mikula (bio)The following testimonials were offered on the occasion of a memorial gathering for Dr. Lewis E. Hahn held on February 19, 2005, and were compiled for presentation here by Sharon (Hahn) Crowell.A Tribute to Dr. Lewis E. Hahn (1908-2004) from a Global PerspectiveGeorge C. H. Sun President, Thomé H. Fang Institute, Inc., Mobile, AlabamaAmong the philosophical community in both the East and the West, no word of introduction is needed for our beloved Master, who was the recipient of numerous distinctions and honors, with titles that included "Man of the Year in Philosophy" and "Award of Lifetime Achievement." The very name "Lewis E. Hahn" itself already stands now for genuineness, dedication, and fulfillment.A great work is a dialogue with eternity; a great person is such a work. In less than thirty years he succeeded in developing Carbondale from what had been a small college town in the Midwest into the Mecca of American philosophy. His most important achievements were the Dewey Center and the Pepper Archives that he helped install at SIUC These, among other such institutions, will remain a unique contribution, a glory of American philosophy, and a monument in the history of human thought.For posterity Lewis E. Hahn will remain an object of wonder and amazement. How is it possible for one human being to have accomplished so much, so well, and in so short a span of time—less than one century—in breadth, depth, and diversity? Some one hundred years ago, by bridging the gap between the New World and the Old, William James was hailed as the great genius of international friendship among philosophical thinkers, but we now find a greater genius in Lewis E. Hahn, who succeeded in bringing together the peoples of East and West from at least four continents: Europe, Australia, America (both North and Latin America), and Asia. To my knowledge, few of his predecessors and contemporaries have been half so widely read and liberal-minded as he was, in view of the range and scope of the Library of Living Philosophers that he helped continue after the passing of its founder, Dr. Paul A. Schilpp.What type of man was Hahn, our younger generation will wonder? Only a pluralist approach can help us understand the true character of such a legendary pluralist-contextualist. In short, he was "a full personality." As I recall, while working on my dissertation with him in the 1970s, we had a brief discussion on Confucius, the sage of ancient China. "A full personality!" was his laconic assessment. Suddenly I realized, to quote the Analects: "The Master is talking about himself!" For, as the Buddhists put it, only a Buddha can understand a Buddha. Or, as William James put it, only one who has philosophy can appreciate philosophy. Many friends [End Page 1] of my generation admire him so much; Te Chen of Hong Kong calls him "a great Confucian in America." Those who regret the loss of many precious Confucian virtues in China today have now rediscovered them in the person of Lewis E. Hahn! If Nietzsche called Kant "a great Chinese in Königsberg," it is simply because he had not encountered our own Master.A paradigm of academic leadership, Dr. Hahn is simply irreplaceable—this is a tribute I personally heard in Carbondale in the late 1960s. It is not an exaggeration to say that he was a superb administrator, and he could have been the best Secretary of the State we ever had, for he possessed more in the way of philosophical wisdom than all his predecessors put together! As a great teacher, he was no less "serene, good, learned, wise, and ardent" than... (shrink)

In the present study, we use a training design in two experiments to examine whether bilingual language switching facilitates two components of cognitive control, namely monitoring and inhibitory control. The results of Experiment 1 showed that training in language switching reduced mixing costs and the anti-saccade effect among bilinguals. In Experiment 2, the findings revealed a greater decrease of mixing costs and a smaller decrease of the anti-saccade effect from pre- to post-training for the language switching training group compared to (...) the L2 training group. Overall, the results suggest that extensive exercise in monitoring and inhibitory control among languages in an experimental setting may enhance the corresponding components of cognitive control. We discuss these findings in the context of the relationship between bilingual language control and executive control. (shrink)

This book is both a history of philosophy of logic told from the Kantian viewpoint and a reconstruction of Kant’s theory of logic from a historical perspective. Kant’s theory represents a turning point in a history of philosophical debates over the following questions. (1) Is logic a science, instrument, standard of assessment, or mixture of these? (2) If logic is a science, what is the subject matter that differentiates it from other sciences, particularly metaphysics? (3) If logic is a necessary (...) instrument to all philosophical inquiries, how is it so entitled? (4) If logic is both a science and an instrument, how are these two roles related? Kant’s official answer to these questions centers on three distinctions: general versus particular logic; pure versus applied logic; pure general logic versus transcendental logic. The true meaning and significance of each distinction becomes clear, I argue, only if we consider two factors. First, Kant was mindful of various historical views on how logic relates to other branches of philosophy (viz. metaphysics and physics) and to the workings of common human understanding. Second, he first coined ‘transcendental logic’ while struggling to secure metaphysics as a proper “science,” and this conceptual innovation would in turn have profound implications for his mature theory of logic. Against this backdrop, I reassess the place of Kant’s theory in the history of philosophy of logic and highlight certain issues that are still debated today, such as normativity of logic and the challenges posed by logical pluralism. In Chapter 1, “Kant and a Philosophical History of Logic – Methodological Reflections,” I discuss certain exegetical challenges posed by Kant’s logic corpus and argue for a “history of philosophical problems” method by which to reconstruct a Kantian theory of logic. In Chapter 2, “The Nature and Place of Logic – A History of Controversies,” I construct a partial history of philosophy of logic that revolves around the (supposedly) scientific status of logic on the one hand and its value or utility on the other. In Chapter 3, “The Making of a Scientific Logic from Bacon to Wolff,” I examine how four representative early modern philosophers – Francis Bacon, John Locke, G.W. Leibniz, and Christian Wolff – approached the four questions mentioned above. In Chapter 4, “Kant on the Way to His Own Philosophy of Logic,” I consider how Kant, in the decade between around mid-1760s and mid-1770s, navigated between existing accounts of logic until he finally found his own voice. I highlight the breakthroughs that would mark his critical departures from previous views and pave the way for the final articulation of his own view. In Chapter 5, “Logic and the Demands of Kantian ‘Science’,” I zero in on Kant’s official theory of logic in his monumental publication, Critique of Pure Reason. I foreground both what makes the theory original and what leaves it vulnerable to criticisms from post-Kantian thinkers. (shrink)

John Venn has the “uneasy suspicion” that the stagnation in mathematical logic between J. H. Lambert and George Boole was due to Kant’s “disastrous effect on logical method,” namely the “strictest preservation [of logic] from mathematical encroachment.” Kant’s actual position is more nuanced, however. In this chapter, I tease out the nuances by examining his use of Leonhard Euler’s circles and comparing it with Euler’s own use. I do so in light of the developments in logical calculus from G. W. (...) Leibniz to Lambert and Gottfried Ploucquet. While Kant is evidently open to using mathematical tools in logic, his main concern is to clarify what mathematical tools can be used to achieve. For without such clarification, all efforts at introducing mathematical tools into logic would be blind if not complete waste of time. In the end, Kant would stress, the means provided by formal logic at best help us to express and order what we already know in some sense. No matter how much mathematical notations may enhance the precision of this function of formal logic, it does not change the fact that no truths can, strictly speaking, be revealed or established by means of those notations. (shrink)

The studies of urban popular culture in modern China in recent years have attracted wide attention from scholars in China and abroad. The symposium, which is composed by Ma Min’s “Injecting vitality into the studies of urban cultural history,” Jiang Jin’s “Issues in the studies of urban popular culture in modern China,” Wang Di’s “The microcosm of Chinese cities: The perspective and methodology of studying urban popular culture from the case of teahouses in Chengdu,” Joseph W. Esherick’s “Remaking the Chinese (...) city: Urban space and urban culture” and Lu Hanchao’s “From elites to common people: The downward trend in the studies of Chinese urban history in the United States,” provide valuable insights on the perspective, trend, and methodology of the studies. (shrink)

In analyzing S0009838800019480_inline1 for composition I start in the most obvious way with S0009838800019480_inline2 in the sense of ‘gang’ , while S0009838800019480_inline3 must be a root-noun from *lew-s, and is perhaps immediately cognate with Skr. lu-nati ‘caedit.’1 This analysis makes S0009838800019480_inline4 mean something like ‘ uiam-muniens,’ i.e. a sort of ‘ ponti-fex.’ I think more particularly of the sacrificial leader, the S0009838800019480_inline5, the Rex Sacrificulus, who, while he may have been concerned with the making of ways on earth, also made (...) paths for man to the gods. But this aside, he who ‘ blazed the trail,’ who ‘ loosed’ or ‘ solved ’ the ‘ ways,’ was ‘ explorer, guide, leader,’ i.e. ‘dux.’. (shrink)

This book collects essays from the 2006 and 2007 International Philosophy Colloquia Evian, centred around a central problem in the philosophy of mind: the relationship between the human faculty of sensory experience and the faculty of conceptual reflection, that is self-consciousness. Containing articles by philosophers of eight nationalities, in three languages (English, French, German), and of "analytical" as well as "continental" provenance, it beautifully represents the spirit of the colloquia. Authors include Joshua Andresen (AU Beirut), Valérie Aucouturier (Kent U / (...) U Paris I), Karin de Boer (KU Leuven), Santiago Echeverri (U Genève), Roberto Farneti (LU Bolzano), Tim Henning (JLU Giessen), Felix Koch (Columbia U), Christophe Laudou (Madrid), David Lauer (FU Berlin), Jason Leddington (Bucknell U), Nicolas Monseu (UC Louvain), Soraya Nour (HU Berlin), Hans Bernhard Schmid (U Wien), Henning Tegtmeyer (U Leipzig). (shrink)

译自: Vorlesungen uber die Geschichte der Philosophie/G. W. F. Hegel. -- Stuttgart: Fr. Frommanns Verlag., 1928. -- 书末附: 专名索引. -- 书脊题: 汉译名著.

Artykuł przedstawia Deborę Vogel jako jedną z najważniejszych krytyczek i teoretyczek sztuki lat trzydziestych XX wieku. Po polsku oraz w jidysz stworzyła ona system, w którym sztuka jawi się jako poetycko-programowa reakcja na rzeczywistość. Jest ona elitarna, ale też ściśle związana z codziennością. Jest niezbędna dla życia, ale też jest „samym życiem”, w sensie banalnej i wiecznej ballady. Za tą konstrukcją myślową kryje się malarstwo Marca Chagalla. To na przykładzie jego obrazów Vogel dowodzi głównej tezy awangardy o jedności formy i (...) treści. Na tożsamość życia i sztuki Vogel spogląda przez pryzmat aktualności rozumianej nie jako manifestowanie poglądów politycznych, lecz jako konstruowanie rzeczywistości w dziele sztuki. Punktem wyjścia jest dla lwowskiej intelektualistki estetyka Hegla, od której stopniowo przesuwa się ku dialektyce materialistycznej, rozwijając m. in. tezy Lu Märten, pionierki estetyki marksistowskiej. Poetyka życia oraz koncepcje sztuki były u Vogel szeroko zakorzenione w filozofii, m.in. w teorii subiektywnego postrzegania Jakoba von Uexkülla. W artykule omówiona zostaje jego koncepcja koła funkcjonalnego, jak i mająca duży wpływ na artystów awangardowych teza, iż rzeczywistość stanowi dla indywiduum wyłącznie konstrukcję własnych doznań zmysłowych. Na koniec stawiane są pytania dotyczące znaczenia myśli Bergsona i Simmla dla rozumienia sztuki w ujęciu proponowanym przez Deborę Vogel. (shrink)

The study of Joseon 朝鮮 Neo-Confucianism has recently given some attention to an inclination toward the Learning of the Mind-Heart, and Yi Gan 李柬 is at the center of this research. He was an outstanding disciple of Gwon Sang-ha 權尙夏 and a successor to the philosophical spirit of the Yulgok 栗谷 School; he is renowned for initiating the Horak 湖洛 Debate through his controversies with Han Won-jin 韓元震. In “A Thesis on the Not-Yet-Aroused State,” Yi asserted that the mind-heart is (...) purely good, basing his argument on the doctrine that “li 理 and qi 氣 are actualized as the same entity, and the mind-heart and nature are united as one.” Han Won-jin criticized this assertion as belonging to the Lu-Wang 陸王 School of Neo-Confucianism, and in fact, Yi Gan’s arguments were, in some aspects, consistent with Wang Yangming’s 王陽明 philosophy of the mind-heart. Indisputably, however, Yi Gan was an ardent follower of Zhu Xi’s 朱熹 philosophy. In this case, Yi Gan’s inclination toward the Learning of the Mind-Heart may perhaps be viewed in the tradition of the Learning of the Way, which emphasized self-cultivation and practice, a distinct feature of Joseon Neo-Confucianism. (shrink)

Le large sujet annoncé par le titre de ce livre laisse entendre, pour qui fréquente un peu la philosophie médiévale, que nous allons être informés des vues les plus récentes sur ce problème que posent les textes philosophiques médiévaux, dont on ne dispose souvent pas d’éditions scientifiques, dont l’édition scientifique ellemême pose problème, textes qui appartiennent à une épistèmè si radicalement différente de la nôtre qu’il est légitime de penser que toute interprétation contemporaine va irrémédiablement en escamoter un caractère essentiel. (...) Ce qui pose, on le devine, le problème de la possibilité de la traduction. Éditer, c’est déjà interpréter. Traduire aussi. N’en déplaise aux éditeurs, l’interprétation est toujours première. Interpréter, éditer, traduire, d’Étienne Gilson à Lambert-Marie de Rijk, de Lambert-Marie De Rijk à Alain de Libera et Claude Panaccio ces questions sont au cœur de l’activité de l’historien de la philosophie médiévale. Cette problématique essentielle n’est, nous le concédons, pas absente de l’ouvrage. J. Brams, C. Burnett, et dans une moindre mesure J. Decorte y font écho. Hélas, en nous laissant une impression de déjà lu. Cette constatation nous mène au cœur du malaise que provoque cet ouvrage. Le lecteur pressé risque de ne pas s’attarder sur les deux pages et dix lignes qui constituent la préface maladroite du livre et de garder ainsi l’impression d’avoir entre les mains les actes d’un colloque scientifique. Qu’il se détrompe! Les textes réunis ici ont été lus à Louvain-la-Neuve lors d’un séminaire de troisième cycle devant une poignée d’étudiants. Autant dire que la plupart des collaborateurs se sont contentés, comme de juste, d’exposer les résultats de travaux déjà anciens. Mais quel est l’intérêt de publier ces textes? (shrink)

In einem Brief nennt Adorno die "Negative Dialektik" kurz nach ihrem Erscheinen unter seinen Schriften "das philosophische Hauptwerk, wenn ich so sagen darf“. Dieser herausgehobenen Bedeutung, die das Werk für Adorno hatte, entspricht nicht nur die lange Zeit, die er mit der Abfassung des Buchs beschäftigt war, sondern auch die lange Geschichte, die ihre zentralen Motive in seinem Denken haben. Philosophische Begriffsklärung, die Arbeit an "Begriff und Kategorien“ einer negativen Dialektik, versteht Adorno dabei als dialektischen Übergang in inhaltliches Denken – (...) und so betreibt er sie auch hier. Das hat Konsequenzen für die Form des kooperativen Kommentars, der in diesem Band versucht wird. Adornos "Negative Dialektik" zu kommentieren, kann nur in dem Bewußtsein der unüberbrückbaren Kluft gelingen, die den Kommentar von diesem Text trennt. (shrink)

Celem niniejszego artykułu jest wykładnia Jeana-Lu ca Mariona fenomenologii donacji jako swoistej filozoficznej teorii performansu. Inspiracje, kierunek oraz kontekst przedstawionej interpretacji wyznaczają istotne przeobrażenia współczesnej humanistyki, której krajobraz został ukształtowany przez liczne kontrtekstualne zwroty. Artykuł przedstawia główne motywy Marionowskiej fenomenologii donacji, takie jak kontrmetoda, dar, sakrament, objawienie, oddany, wydarzenie, przygodność, fenomen nasycony, świadek itp., doszukując się w nich performatywnych instrukcji. Artykuł kończy się wielowątkową krytyką Mariona fenomenologii donacji, pokazując dlaczego nie zdaje ona egzaminu i musi ustąpić fenomenologicznej zasadzie performancji.

The following is the transcript of a lecture taken in shorthand by Hans-Georg Backhaus. The transcript was originally published as an appendix in Hans-Georg Backhaus, Dialektik der Wertform. Untersuchungen zur marxschen Ökonomiekritik, a complete translation of which is forthcoming in the Historical Materialism book series.

Young and colleagues . Betwixt life and death: case studies of the Cotard delusion. In P. W. Halligan & J. C. Marshall , Method in madness: Case studies in cognitive neuropsychiatry. Mahway, NJ: Lawrence Erlbaum Associates.) have suggested that cases of the Cotard delusion result when a particular perceptual anomaly occurs in the context of an internalising attributional style. This hypothesis has not previously been tested directly. We report here an investigation of attributional style in a 24-year-old woman with Cotard (...) delusion . LU’s attributional style was assessed using the Internal, Personal and Situational Attributions Questionnaire . A new measure of causal locus: the internal, personal and situational attributions questionnaire. Personality and Individual Differences, 20, 261–264.). LU showed a significantly greater proportion of internalising attributions than the control group, both overall and for negative events specifically. The results obtained thus support an association of Cotard delusion with an internalising attributional style, and are therefore consistent with the account of Young and colleagues. The potential brain basis of Cotard delusion is discussed. (shrink)

Rombach, H. Die Gegenwart der Philosophie.--Möller, J. Philosophie als Antihumanismus?--Schaeffler, R. Zum Verhältnis von transzendentaler und historischer Reflexion.--Balmer, H. P. Produktivität und Rezeptivität.--Marx, W. Das Bedürfnis der Philosophie.--Mader, J. Philosophie als Kritik.--Hommes, U. Sein und Sinn.--Sobrevilla, D. Ortega und der deutsche Idealismus.--Kohlenberger, H. Robert Musils philosophischer Anspruch.--Schwartländer, J. Die Menschenrechte und die Notwendigkeit einer praktischen Weltorientierung.--Heintel, E. Vom Sinn der Freundschaft.--Oeser, E. Die wissenschaftstheoretische Wende der Philosophie.--Simon, J. Zu einem philosophischen Begriff der Kausalität.--Schäfer, L. Der wissenschaftstheoretische Status synthetischer Urteile a (...) priori.--Lütterfelds, W. Das kategoriale Apriori des Erfahrungsfortschritts. (shrink)

Previous studies of the lexical psycholinguistic properties in second language production have assessed the degree of an LPP dimension of an L2 corpus by computing the mean ratings of unique content words in the corpus for that dimension, without considering the possibility that learners at different proficiency levels may perceive the degree of that dimension of the same words differently. This study extended a dynamic semantic similarity algorithm to estimate the degree of five different LPP dimensions of several sub-corpora of (...) the Education First-Cambridge Open Language Database representing L2 English learners at different proficiency levels. Our findings provide initial evidence for the validity of the algorithm for assessing the LPPs in L2 production and contribute useful insights into between-proficiency relationships and cross-proficiency differences in the LPPs in L2 production as well as the relationships among different LPP dimensions. (shrink)